abstract：OBJECTIVE:To determine the efficacy and tolerability of citalopram when compared to other antidepressants for late-life depression (LLD). METHODS:We searched electronic databases and trial registries to identify randomized controlled trials comparing citalopram to other antidepressants for LLD. Study quality was asses...

journal_title：International journal of geriatric psychiatry

authors： Seitz DP,Gill SS,Conn DK

更新日期：2010-12-01 00:00:00

abstract：OBJECTIVE:To consider the characteristics of first episode psychosis in older adults in a county in North East England. METHOD/DESIGN:The present study used a naturalistic design to compare individuals aged 65 years and over with those under 65, with a first episode psychosis. Data were collected on demographics, diag...

journal_title：International journal of geriatric psychiatry

authors： Mitford E,Reay R,McCabe K,Paxton R,Turkington D

更新日期：2010-11-01 00:00:00

abstract：AIM:To determine rates of cerebral atrophy in individuals with symptoms of memory loss but no objective cognitive impairment (SNCI) and their association with future cognitive decline. METHODS:Thirty-two SNCI subjects, 16 with mild cognitive impairment (MCI) and 27 control subjects had clinical assessment and magnetic...

journal_title：International journal of geriatric psychiatry

authors： Archer HA,Kennedy J,Barnes J,Pepple T,Boyes R,Randlesome K,Clegg S,Leung KK,Ourselin S,Frost C,Rossor MN,Fox NC

更新日期：2010-11-01 00:00:00

abstract：OBJECTIVE:To determine whether attentional impairments are reliable neuropsychological markers of sub syndrome delirium. METHOD:A prospective cohort study with repeated assessment beginning pre-operatively and continuing through the first post-operative week. Computerized assessments of attention and the Mini-Mental S...

journal_title：International journal of geriatric psychiatry

authors： Lowery DP,Wesnes K,Brewster N,Ballard C

更新日期：2010-10-01 00:00:00

abstract：OBJECTIVES:Physical symptoms are known to be associated with late life depression both cross-sectionally and over time. We attempted to determine if self-reported shortness of breath (SoB) is associated with depressive symptoms at long-term (3-year) follow-up in a community sample of older (65+) adults. METHODS:A samp...

journal_title：International journal of geriatric psychiatry

authors： Blazer DG,Hybels CF

更新日期：2010-10-01 00:00:00

abstract：OBJECTIVE:To examine the utility of a brief, metacognition questionnaire by examining its association with objective cognitive testing and informant ratings. We hypothesized that the association between self-ratings of change and both outcomes would be greater among individuals without dementia than among those with de...

journal_title：International journal of geriatric psychiatry

authors： Buckley T,Norton MC,Deberard MS,Welsh-Bohmer KA,Tschanz JT

更新日期：2010-07-01 00:00:00

abstract：OBJECTIVE:To review non-drug treatments for dementia; to provide a source of evidence for informal carers who want ideas about non-drug approaches for dementia, that they might try or that they could try to access. The systematic review addresses: what non-drug treatments work and what do they work for? What non-drug t...

journal_title：International journal of geriatric psychiatry

authors： Hulme C,Wright J,Crocker T,Oluboyede Y,House A

更新日期：2010-07-01 00:00:00

abstract：OBJECTIVES:In primary care 50-95% of patients with depression present with vegetative symptoms (VS). Based on the extant literature, older adults showing VS (but no dysphoria) may show functional impairment but this hypothesis has not been empirically tested. The goal of this study was to examine neurocognitive and dai...

journal_title：International journal of geriatric psychiatry

authors： Paradiso S,Duff K,Vaidya JG,Hoth A,Mold JW

更新日期：2010-06-01 00:00:00

abstract：OBJECTIVE:To compare performance of patients with mild-moderate Alzheimer's disease (AD) and vascular dementia (VaD) on tests of executive functioning and working memory. METHODS:Patients with AD (n = 76) and VaD (n = 46) were recruited from a memory clinic along with dementia free participants (n = 28). They underwen...

journal_title：International journal of geriatric psychiatry

authors： McGuinness B,Barrett SL,Craig D,Lawson J,Passmore AP

更新日期：2010-06-01 00:00:00

abstract：OBJECTIVE:Alzheimer's disease (AD) is prevalent among elderly people, who often have comorbid conditions, and may be prescribed multiple medications. Drug safety and tolerability is paramount in maximising efficacy and optimising patient and carer quality of life, as patients are vulnerable to adverse events (AEs) and/...

journal_title：International journal of geriatric psychiatry

authors： Jones RW

更新日期：2010-06-01 00:00:00

abstract：PURPOSE:In this study, we explored association between hypertension and depression in the very elderly using a sample ranged in age from 90 to 108 years. METHODS:A cross-sectional study. RESULTS:The sample included 687 unrelated Chinese nonagenarians/centenarians (67.4% women, mean age 93.51 years). The mean depressi...

journal_title：International journal of geriatric psychiatry

authors： Wen Z,Bi-Rong D,Chang-Quan H,Zhen-Chan L,Yuan Z,Hong-Mei W,Yan-Ling Z,Hui W,Ping H

更新日期：2010-06-01 00:00:00

abstract：OBJECTIVE:This study examined the association between a history of heavy alcohol use and smoking, presence of the apolipoprotein-E epsilon 4 allele (APOE epsilon4), and age of disease onset in a community dwelling sample of 685 Alzheimer's disease (AD) patients spanning three ethnic groups. DESIGN:Cross-sectional stud...

journal_title：International journal of geriatric psychiatry

authors： Harwood DG,Kalechstein A,Barker WW,Strauman S,St George-Hyslop P,Iglesias C,Loewenstein D,Duara R

更新日期：2010-05-01 00:00:00

abstract：BACKGROUND:This study aimed to investigate the association of alcohol use disorder (AUD) with four candidate genes in older Korean men: aldehyde dehydrogenase 2 (ALDH2, 1/2), brain-derived neurotrophic factor (BDNF, val66met), serotonin transporter gene linked polymorphic region (5-HTTLPR, s/l), and methylenetetrahydro...

journal_title：International journal of geriatric psychiatry

authors： Shin S,Stewart R,Ferri CP,Kim JM,Shin IS,Kim SW,Yang SJ,Yoon JS

更新日期：2010-05-01 00:00:00

abstract：OBJECTIVE:Rivastigmine, a dual cholinesterase inhibitor (ChEI), is widely approved for the symptomatic treatment of both mild-to-moderate Alzheimer's disease (AD) and Parkinson's disease dementia. Orally administered ChEIs may be associated with gastrointestinal (GI) side effects and add-on therapy with memantine, an N...

journal_title：International journal of geriatric psychiatry

authors： Olin JT,Bhatnagar V,Reyes P,Koumaras B,Meng X,Brannan S

更新日期：2010-04-01 00:00:00

abstract：OBJECTIVE:Although the evidence base for the use of antipsychotics in older people with schizophrenia is generally of low quality, it tends to support the use of atypical antipsychotics. Only limited information regarding longer term adherence to these apparently more effective drugs is available. The aim of this study...

journal_title：International journal of geriatric psychiatry

authors： Ritchie CW,Harrigan S,Mastwyk M,Macfarlane S,Cheesman N,Ames D

更新日期：2010-04-01 00:00:00

abstract：OBJECTIVE:To pilot a three-step diagnostic model for young and old patients with Parkinson's disease dementia (PDD). METHODS:Prospective investigator-blinded study. We developed a screening questionnaire for patients with Parkinson's disease (PD) and their caregivers. Further, patients were subjected to three screenin...

journal_title：International journal of geriatric psychiatry

authors： Robben SH,Sleegers MJ,Dautzenberg PL,van Bergen FS,ter Bruggen JP,Rikkert MG

更新日期：2010-03-01 00:00:00

abstract：OBJECTIVE:Elderly persons with mild cognitive impairment (MCI) are at increased risk of dementia and functional impairments. The present study investigated the contribution of three domains of executive cognition to everyday functioning among persons with MCI. METHODS:124 MCI patients and 68 cognitively normal elderly...

journal_title：International journal of geriatric psychiatry

authors： Aretouli E,Brandt J

更新日期：2010-03-01 00:00:00

abstract：OBJECTIVES:To explore the extent of and factors associated with male residents who change wandering status post nursing home admission. DESIGN:Longitudinal design with secondary data analyses. Admissions over a 4-year period were examined using repeat assessments with the Minimum Data Set (MDS) to formulate a model un...

journal_title：International journal of geriatric psychiatry

authors： King-Kallimanis B,Schonfeld L,Molinari VA,Algase D,Brown LM,Kearns WD,Davis DM,Werner DH,Beattie ER,Nelson AL

更新日期：2010-02-01 00:00:00

abstract：OBJECTIVES:To investigate the relation of plasma levels of Abeta peptides (Abeta1-40 and Abeta1-42) and apolipoprotein E (APOE) genotype to dementia status, and the duration of Alzheimer's disease (AD) in adults with Down syndrome (DS). METHODS:Adults with DS were recruited from community settings and followed up for ...

journal_title：International journal of geriatric psychiatry

authors： Prasher VP,Sajith SG,Mehta P,Zigman WB,Schupf N

更新日期：2010-02-01 00:00:00

abstract：BACKGROUND:The mini-mental state exam (MMSE) has been used to address questions such as determination of appropriate cutoff scores for differentiation of individuals with intact cognitive function from patients with dementia and rate of cognitive decline. However, little is known about the relationship of performance i...

journal_title：International journal of geriatric psychiatry

authors： Guerrero-Berroa E,Luo X,Schmeidler J,Rapp MA,Dahlman K,Grossman HT,Haroutunian V,Beeri MS

更新日期：2009-12-01 00:00:00

abstract：OBJECTIVE:To assess the cost effectiveness of cholinesterase inhibitor (ChEI) treatment in patients with Alzheimer's disease (AD) and Dementia with Lewy bodies (DLB). METHOD:We used 4-month open label follow-up data from routine memory clinic patients. There were 852 patients with AD and 112 with DLB. We applied three...

journal_title：International journal of geriatric psychiatry

authors： Gustavsson A,Van Der Putt R,Jönsson L,McShane R

更新日期：2009-10-01 00:00:00

abstract：BACKGROUND:Depression is a frequent problem in stroke patients but, all too often, the problem goes unrecognized. How depression-like symptoms in post-stroke depression (PSD) should be interpreted is still subject to debate. If PSD has a distinct symptom profile of depression accompanying other chronic vascular somatic...

journal_title：International journal of geriatric psychiatry

authors： Bour A,Rasquin S,Aben I,Strik J,Boreas A,Crijns H,Limburg M,Verhey F

更新日期：2009-10-01 00:00:00

abstract：OBJECTIVES:To examine the clinical differences between late-onset schizophrenia (LOS) and early-onset schizophrenia (EOS) in Taiwanese elderly chronic hospitalized schizophrenic patients. METHODS:By using a cross-sectional study method, we investigated all the hospitalized elderly schizophrenic patients in a general h...

journal_title：International journal of geriatric psychiatry

authors： Huang C,Zhang YL

更新日期：2009-10-01 00:00:00

abstract：OBJECTIVES:This study compares inter- and intra-country differences in the prevalence of physical restraints and antipsychotic medications in nursing homes, and examines aggregated resident conditions and organizational characteristics correlated with these treatments. METHODS:Population-based, cross-sectional data we...

journal_title：International journal of geriatric psychiatry

authors： Feng Z,Hirdes JP,Smith TF,Finne-Soveri H,Chi I,Du Pasquier JN,Gilgen R,Ikegami N,Mor V

更新日期：2009-10-01 00:00:00

abstract：OBJECTIVE:The authors examine changes in psychiatric referral patterns for geriatric inpatients since last reported in the United States, more than 20 years ago, and compare geriatric psychiatric referrals to those of a non-geriatric cohort. METHOD:Retrospective study comparing psychiatric diagnosis, treatment and aft...

journal_title：International journal of geriatric psychiatry

authors： Schellhorn SE,Barnhill JW,Raiteri V,Faso VL,Ferrando SJ

更新日期：2009-10-01 00:00:00

abstract：BACKGROUND:The management of Behavioural and Psychological Symptoms of Dementia (BPSD) has been the subject of considerable debate over the last few years in view of the poor evidence base for pharmacological agents and concerns about their safety. OBJECTIVES:This study sought to obtain expert opinion on the managemen...

journal_title：International journal of geriatric psychiatry

authors： Bishara D,Taylor D,Howard RJ,Abdel-Tawab R

更新日期：2009-09-01 00:00:00

abstract：OBJECTIVE:Studies have shown that psychological problems in elderly patients are often unrecognised in primary care. The aim of this study was to investigate the quality of life and consultation rates of Chinese elderly patients with unrecognised psychological problems in primary care. The prevalence and risk factors o...

journal_title：International journal of geriatric psychiatry

authors： Lam CL,Chin WY,Lee PW,Lo YY,Fong DY,Lam TP

更新日期：2009-09-01 00:00:00

abstract：OBJECTIVE:To derive norms for the Mini Mental State Examination (MMSE) based on age, gender and level of formal education among the elderly in Sri Lanka. METHOD:A validated Sinhalese version of the MMSE was administered to people aged 55 years and above residing in 14 randomly selected elders' homes. Effects of age, g...

journal_title：International journal of geriatric psychiatry

authors： De Silva R,Disanayaka S,De Zoysa N,Sanjeewanie N,Somaratne S,Foster J,Srikanth S,Kathriarachchi ST,Martins RM

更新日期：2009-07-01 00:00:00

abstract：OBJECTIVES:The post-hoc analyses reported here evaluate the specific effects of memantine treatment on ADAS-cog single-items or SIB subscales for patients with moderate to severe AD. METHODS:Data from six multicentre, randomised, placebo-controlled, parallel-group, double-blind, 6-month studies were used as the basis ...

journal_title：International journal of geriatric psychiatry

authors： Mecocci P,Bladström A,Stender K

更新日期：2009-05-01 00:00:00

abstract：BACKGROUND:The paper explores the diverse ethical issues in the care of persons with dementia, in the Netherlands and Kerala, India. These cross-cultural data are used to suggest newer ways for addressing the ethical issues in a mutually enhancing manner. METHODS:A thorough review of the literature focusing on ethical...

journal_title：International journal of geriatric psychiatry

authors： Sowmini CV,De Vries R

更新日期：2009-04-01 00:00:00

abstract：OBJECTIVE:Limited data are available on how older adults access public mental health systems. This study examines how uninsured or publicly insured older adults with severe mental illness in San Diego County initially accessed the public mental health system, as well as their subsequent use of public mental health serv...

journal_title：International journal of geriatric psychiatry

authors： Gilmer TP,Ojeda VD,Fuentes D,Criado V,Garcia P

更新日期：2009-03-01 00:00:00

abstract：OBJECTIVE:An economic evaluation of dementia-related interventions from a societal perspective should take account of informal caregiving. We assessed informal caregiving time and report our findings on the validity and stability of our results. METHODS:Within the German IDA study ('Dementia Care Initiative in Primary...

journal_title：International journal of geriatric psychiatry

authors： Neubauer S,Holle R,Menn P,Grässel E

更新日期：2009-03-01 00:00:00

abstract：OBJECTIVE:Memory complaints in the absence of objective test impairments are common. Only a subset of these subjects seeks medical attention for these complaints. The aim of the present study was to investigate which factors determine why people with subjective memory complaints (SMC) seek medical attention. METHODS:T...

journal_title：International journal of geriatric psychiatry

authors： Ramakers IH,Visser PJ,Bittermann AJ,Ponds RW,van Boxtel MP,Verhey FR

更新日期：2009-02-01 00:00:00

abstract：OBJECTIVE:Cross validation study of the MoCA for the detection of Alzheimer's disease (AD) and Mild Cognitive Impairment (MCI) in a community-based cohort residing in the Southeastern United States. METHODS:One hundred and eighteen English-speaking older adults, who underwent diagnostic evaluation as part of an on-goi...

journal_title：International journal of geriatric psychiatry

authors： Luis CA,Keegan AP,Mullan M

更新日期：2009-02-01 00:00:00

abstract：OBJECTIVE:To determine whether attentional impairments are reliable neuropsychological markers of delirium. METHOD:A prospective cohort of one hundred patients admitted for elective orthopaedic surgery, 70 years and over, and free of dementia were recruited from an Orthopaedic unit in a university teaching hospital. C...

journal_title：International journal of geriatric psychiatry

authors： Lowery DP,Wesnes K,Brewster N,Ballard C

更新日期：2008-12-01 00:00:00

abstract：BACKGROUND/OBJECTIVE:Dementia is under-diagnosed in primary care. This study investigated whether an in-home geriatric assessment and management programme could improve the identification of patients with dementia in primary care. METHODS:A secondary analysis was performed, using data of a randomised controlled trial ...

journal_title：International journal of geriatric psychiatry

authors： Perry M,Melis RJ,Teerenstra S,Drasković I,van Achterberg T,van Eijken MI,Lucassen P,Rikkert MG

更新日期：2008-12-01 00:00:00

abstract：BACKGROUND:This paper provides an initial evaluation of the impact of the Single Assessment Process (SAP) in England upon practice regarding multidisciplinary assessment. OBJECTIVES:To investigate changes in recorded health needs of older people and in the number of multidisciplinary assessments undertaken using socia...

journal_title：International journal of geriatric psychiatry

authors： Sutcliffe C,Hughes J,Abendstern M,Clarkson P,Challis D

更新日期：2008-12-01 00:00:00

abstract：OBJECTIVE:The study objective is to evaluate the use of qEEG data for the cross-sectional differentiation of mild cognitive impairment (MCI) from mild Alzheimer's disease (AD) and in the longitudinal prediction of cognitive decline in MCI. METHODS:Eighty-eight subjects with MCI and 42 subjects with mild probable AD we...

journal_title：International journal of geriatric psychiatry

authors： Luckhaus C,Grass-Kapanke B,Blaeser I,Ihl R,Supprian T,Winterer G,Zielasek J,Brinkmeyer J

更新日期：2008-11-01 00:00:00

abstract：OBJECTIVE:The purpose of this study was to explore the effects of demographic variables on Stroop Color and Word Test (SCWT) performance in an educationally diverse elderly population and to provide normative information. METHODS:SCWT was administered to 564 community-dwelling volunteers aged 60-90 years with an educa...

journal_title：International journal of geriatric psychiatry

authors： Seo EH,Lee DY,Choo IH,Kim SG,Kim KW,Youn JC,Jhoo JH,Woo JI

更新日期：2008-10-01 00:00:00

abstract：BACKGROUND:Despite modest efficacy, unpredictable individual utility, and a high rate of adverse effects, behavioural and psychological symptoms of dementia (BPSD) are common determinants for antipsychotic drug therapy in nursing home patients. AIMS:To explore the impact on BPSD of stopping long-term antipsychotic tre...

journal_title：International journal of geriatric psychiatry

authors： Ruths S,Straand J,Nygaard HA,Aarsland D

更新日期：2008-09-01 00:00:00